Adaptimmune Therapeutics PLC is focused on pre-clinical programs, including PRAME and CD70-directed T-cell therapies, and its allogeneic pipeline. PRAME is highly expressed across a range of solid tumors, including ovarian, endometrial, lung and breast cancers. The CD70 program targets the CD70 antigen, which is expressed across a range of hematological malignancies (acute myeloid leukemia and lymphoma) and solid tumors (renal cell carcinoma). It is using TRuC technology to develop a T-cell therapy (ADP-520) against CD70, with membrane bound IL-15 to enhance persistence. ADP-520 is in pre-clinical testing. TRuC technology combines the targeting of CAR-T cells with T-cell TCR signaling.

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Market Closed - Börse Stuttgart 07:04:00 21/05/26 pm AEST			5-day change	1st Jan Change
0.0100 ^EUR	-.--%		-41.18%	-9.09%

19/05	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
18/11	Adaptimmune Therapeutics plc Announces CEO Changes	CI

Market Cap	7.42M 6.41M 6.01M 5.48M 10.32M 708M 10.37M 71.18M 27.79M 358M 27.86M 27.26M 1.19B	P/E 2024	-1.8x	P/E 2025	0.33x
Enterprise Value	-4.45M -3.84M -3.6M -3.29M -6.18M -424M -6.21M -42.66M -16.66M -215M -16.7M -16.33M -712M	EV / Sales 2024	0.34x	EV / Sales 2025	-0.84x
Free-Float	14.03%	Yield 2024 *	-	Yield 2025	-

19/05	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
18/11	Adaptimmune Therapeutics plc Announces CEO Changes	CI
18/11	Adaptimmune Therapeutics plc Announces Leadership Changes	CI
27/10/25	Evaxion Names Helen Tayton-Martin as Chief Executive Officer	MT
27/10/25	Adaptimmune Therapeutics plc(OTCPK:ADAP.Y) dropped from NASDAQ Composite Index	CI
25/10/25	European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading	MT
24/10/25	European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading	MT
23/10/25	European Equities Traded in the US as American Depositary Receipts Rise in Wednesday Trading	MT
22/10/25	European Equities Traded in the US as American Depositary Receipts Decline in Tuesday Trading	MT
21/10/25	Top Midday Decliners	MT
21/10/25	European Equities Close Mostly Higher in Monday Trading; UK Sentiment Sees 'Some of the Gloom Lift'	MT
21/10/25	European Equities Traded in the US as American Depositary Receipts Rise in Monday Trading	MT
20/10/25	Adaptimmune Therapeutics to Voluntarily Delist From Nasdaq	MT

30/07/25	Guggenheim Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
29/07/25	HC Wainwright Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
26/06/25	Mizuho Downgrades Adaptimmune Therapeutics to Neutral From Outperform, Cuts Price Target to $0.50 From $1.50 on Solvency Concerns	MT
27/11/24	Mizuho Cuts Price Target on Adaptimmune Therapeutics to $1.50 From $3, Keeps Outperform Rating	MT
30/07/24	HC Wainwright Starts Adaptimmune Therapeutics With Buy Rating, $4 Price Target	MT

Adaptimmune Therapeutics plc Stock Börse Stuttgart

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473A

US00653A1079

Pharmaceuticals

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Quarterly revenue - Rate of surprise

17/11	Adaptimmune Announces Changes to Board and Executive Leadership Team	NE
20/10/25	Adaptimmune Announces Delisting from Nasdaq	NE
13/08/25	Adaptimmune Reports Q2 Financial Results and Provides Business Update	NE
28/07/25	Adaptimmune Announces Entry into Definitive Agreement for Sale of TECELRA, lete-cel, afami-cel and uza-cel Cell Therapies to US WorldMeds	NE
13/05/25	Adaptimmune Reports Q1 Financial Results and Provides Business Update	NE

31/05/24	Galapagos gaat samenwerken met Adaptimmune
13/04/24	Roche: Genentech met fin à la collaboration avec Adaptimmune Therapeutics
13/04/24	Roche-Tochter Genentech beendet Zusammenarbeit mit Adaptimmune Therapeutics
12/04/23	GSK : Adaptimmune reprend les droits de deux programmes
08/09/21	Aktien Schweiz Schluss: SMI unter Druck

Manager	Title	Age	Since
Christopher Hill CEO	Chief Executive Officer	46	14/11/2025
Juli P. Miller IRC	Investor Relations Contact	-	01/08/2016
Phil Bassett PRN	Corporate Officer/Principal	-	-

Director	Title	Age	Since
Lawrence Alleva CHM	Chairman	76	14/11/2025
Garry Menzel BRD	Director/Board Member	61	01/06/2023
Christopher Hill BRD	Director/Board Member	46	14/11/2025

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Average	-2.17%	-1.20%	+58.93%	+47.51%	43.29B
Weighted average by Cap.	-2.42%	-2.05%	+84.09%	+42.39%

	2024	2025
Net sales	178M 154M 144M 132M 247M 16.98B 249M 1.71B 667M 8.59B 668M 654M 28.49B	5.92M 5.11M 4.79M 4.38M 8.23M 565M 8.27M 56.82M 22.18M 286M 22.24M 21.76M 948M
Net income	-70.81M -61.14M -57.31M -52.32M -98.44M -6.75B -98.92M -679M -265M -3.42B -266M -260M -11.33B	25.21M 21.76M 20.4M 18.62M 35.04M 2.4B 35.21M 242M 94.39M 1.22B 94.63M 92.57M 4.03B
Net Debt	-77.4M -66.82M -62.64M -57.19M -108M -7.38B -108M -742M -290M -3.73B -291M -284M -12.39B	-11.87M -10.25M -9.61M -8.77M -16.5M -1.13B -16.58M -114M -44.45M -572M -44.56M -43.59M -1.9B

1 week	-41.18%
6 months	-68.75%
Current year	-9.09%

1 week	0.01	0.02
1 month	0	0.02
3 years	0	1.64
5 years	0	5.6