Valuation: Septerna, Inc.

Market Cap 1.49B 1.31B 1.22B 1.12B 2.1B 144B 2.13B 14.47B 5.65B 70.64B 5.6B 5.48B 244B P/E 2026 *
-19.1x
P/E 2027 * -13.6x
Enterprise Value 1.14B 1B 934M 857M 1.61B 110B 1.63B 11.09B 4.33B 54.12B 4.29B 4.2B 187B EV / Sales 2026 *
14.9x
EV / Sales 2027 * 14.9x
Free-Float
97.17%
Yield 2026 *
-
Yield 2027 * -
1 day-1.11%
1 week-0.90%
Current month-1.16%
1 month-4.17%
3 months+34.17%
6 months+28.47%
Current year+18.72%
1 week 31.85
Extreme 31.85
35.11
1 month 30.55
Extreme 30.55
38.04
Current year 22.78
Extreme 22.78
38.04
1 year 10.62
Extreme 10.6161
38.04
3 years 4.17
Extreme 4.17
38.04
5 years 4.17
Extreme 4.17
38.04
10 years 4.17
Extreme 4.17
38.04
Manager TitleAgeSince
Chief Executive Officer 60 01/11/2021
Director of Finance/CFO 55 06/01/2025
President 58 01/08/2025
Director TitleAgeSince
Director/Board Member 60 01/11/2021
Chairman 50 01/11/2021
Director/Board Member 41 01/11/2021
Date Insider Type Main position Quantity % Market Cap.
15/7/26 Fiscal year

Chairperson

12,000 0.0266%
1/7/26 Fiscal year

Executive/Senior Manager

9,999 0.0222%
29/6/26 Fiscal year

Head of Human Resources

6,534 0.0145%
Change 5-day change 1-year change 3-year change Capi.($)
-1.11%-0.90%+138.47% - 1.49B
+1.07%-3.49%-3.35%+10.44% 46.86B
+0.25%+1.65%+399.22%+634.87% 40.23B
-0.27%+4.45%+11.81%+65.64% 36.23B
+0.35%+0.87%+4.46%-10.16% 34.72B
+3.14%+1.02%+4.76%+40.92% 27.89B
-0.73%+11.84%+34.39%+134.36% 16.79B
+0.47%-2.74% - - 16.74B
+0.42%-5.52%-3.43%+9.03% 13.12B
-2.68%-2.49%-11.36%-33.61% 12.7B
Average +0.09%+0.66%+63.89%+106.44% 24.68B
Weighted average by Cap. +0.47%+0.90%+74.83%+136.27%

Financials

2026 *2027 *
Net sales 76.91M 67.55M 62.82M 57.65M 108M 7.41B 110M 746M 291M 3.64B 289M 283M 12.59B 65.83M 57.82M 53.77M 49.34M 92.71M 6.34B 94.14M 639M 249M 3.12B 247M 242M 10.78B
Net income -68.86M -60.48M -56.24M -51.61M -96.97M -6.63B -98.46M -668M -261M -3.26B -258M -253M -11.27B -122M -108M -100M -91.78M -172M -11.79B -175M -1.19B -464M -5.8B -460M -450M -20.04B
Net Debt -349M -306M -285M -262M -491M -33.6B -499M -3.38B -1.32B -16.52B -1.31B -1.28B -57.11B -508M -447M -415M -381M -716M -48.96B -727M -4.93B -1.93B -24.07B -1.91B -1.87B -83.23B
Logo Septerna, Inc.
Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
Employees
130
Date Price Change Volume
24/07/26 USD 33.10 -1.11% 242,035
23/07/26 USD 33.47 -2.13% 298,231
22/07/26 USD 34.20 +1.54% 264,140
21/07/26 USD 33.68 +4.56% 215,407
20/07/26 USD 32.21 -3.56% 197,247
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
10
Last Close Price
33.10USD
Average target price
45.00USD
Spread / Average Target
+35.95%

Quarterly revenue - Rate of surprise

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