Valuation: Ionis Pharmaceuticals, Inc.

Capitalization 12.43B 10.56B 9.75B 9.19B 17.05B 1,157B 17.34B 114B 44.78B 557B 46.64B 45.67B 1,979B P/E ratio 2026 *
-18.4x
P/E ratio 2027 * -67.3x
Enterprise value 12.05B 10.23B 9.45B 8.91B 16.53B 1,121B 16.81B 111B 43.41B 539B 45.21B 44.27B 1,918B EV / Sales 2026 *
14.6x
EV / Sales 2027 * 8.43x
Free-Float
99.23%
Yield 2026 *
-
Yield 2027 * -
1 day-0.08%
1 week+0.03%
Current month+0.14%
1 month+3.96%
3 months-3.01%
6 months+2.88%
Current year-4.95%
1 week 73.9
Extreme 73.905
77.38
1 month 68.9
Extreme 68.9
77.38
Current year 68.9
Extreme 68.9
86.74
1 year 27.9
Extreme 27.9
86.74
3 years 23.95
Extreme 23.95
86.74
5 years 23.95
Extreme 23.95
86.74
10 years 19.59
Extreme 19.5927
86.74
Manager TitleAgeSince
Investor Relations Contact 60 01/07/2012
Chief Executive Officer 64 01/01/2020
Director of Finance/CFO 64 01/05/2000
Director TitleAgeSince
Director/Board Member 71 01/09/2000
Director/Board Member 81 01/01/1994
Director/Board Member 64 13/12/2005
Change 5d. change 1-year change 3-years change Capi.($)
-0.08%+0.03%+164.77%+99.03% 12.43B
+2.22%+5.51%+0.78%-7.93% 47.35B
+1.65%+5.36%+41.25%+23.21% 35.57B
+0.39%+55.82%+308.76%+511.56% 31.16B
+3.56%+6.46%+23.79%-12.08% 28.86B
-0.72%+2.98%+35.64%+28.89% 29.62B
+0.23%+1.60%+47.29%+193.75% 15.01B
+1.20%+4.97%+74.85%+164.95% 14.73B
-4.97%+0.62%+3,684.42%+3,881.33% 15.12B
+0.87%+8.85%+40.89%+13.56% 14.34B
Average +0.31%+9.05%+442.24%+489.63% 24.42B
Weighted average by Cap. +0.63%+10.62%+298.99%+337.17%

Financials

2026 *2027 *
Net sales 827M 703M 649M 612M 1.13B 76.99B 1.15B 7.6B 2.98B 37.04B 3.1B 3.04B 132B 1.41B 1.2B 1.11B 1.04B 1.94B 131B 1.97B 12.97B 5.08B 63.2B 5.3B 5.19B 225B
Net income -665M -564M -521M -491M -911M -61.85B -927M -6.11B -2.39B -29.76B -2.49B -2.44B -106B -211M -179M -165M -156M -289M -19.6B -294M -1.94B -759M -9.43B -790M -774M -33.52B
Net Debt -381M -323M -299M -282M -522M -35.44B -531M -3.5B -1.37B -17.05B -1.43B -1.4B -60.63B -530M -450M -415M -392M -726M -49.29B -739M -4.87B -1.91B -23.71B -1.99B -1.95B -84.32B
Logo Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. is engaged in ribonucleic acid (RNA)-targeted therapeutics. The Company has five marketed medicines and a pipeline in neurology, cardiology, and other areas of high patient need. It has nine medicines in Phase III development and multiple additional medicines in early and mid-stage development. The Company’s products include SPINRAZA, QALSODY, WAINUA, TEGSEDI and WAYLIVRA. SPINRAZA is used for the treatment of patients with spinal muscular atrophy (SMA), a progressive, debilitating and often fatal genetic disease. QALSODY is an antisense medicine that is used for the treatment of adult patients with superoxide dismutase 1 amyotrophic lateral sclerosis (SOD1-ALS), a rare, neurodegenerative disorder that causes progressive loss of motor neurons leading to death. WAINUA is a self-administered subcutaneous LIgand-Conjugated Antisense (LICA) medicine used for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (ATTRv-PN).
Employees
1,402
Date Price Change Volume
18/04/26 75.14 $ -0.17% 393,185
16/04/26 75.26 $ -2.03% 1,873,899
15/04/26 76.82 $ +0.08% 1,288,372
14/04/26 76.76 $ +2.41% 1,595,277
13/04/26 74.95 $ -0.29% 1,650,871
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
A
Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
23
Last Close Price
75.26USD
Average target price
96.73USD
Spread / Average Target
+28.52%

Quarterly revenue - Rate of surprise